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IgG4-Related Disease: From Steroids to Targeted Treatments

January 6, 2025

IgG4-related disease (IgG4-RD) is a curious immune condition. It makes certain organs swell and not work properly. One big clue is that affected organs grow special lymphoid tissues, called TLTs. Inside these, special helper T cells (Tfh2) turn regular B cells into IgG4+ cells, which cause the swell

science

How T-follicular Helper Cells Transform into TR1 Cells

November 22, 2024

Ever wondered how certain T cells can switch their roles in the body? Let's dive into how T-follicular helper (TFH) cells can transform into T-regulatory type 1 (TR1) cells. These changes happen when the body is continuously exposed to foreign substances, a process known as chronic antigenic stimula

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