Salmonella is a sneaky bacteria that can make both animals and humans sick. It's a big deal in the world of food safety. Scientists wanted to dig deeper into the genetic makeup of Salmonella strains that often fly under the radar, especially those from poultry and humans. They looked at 301 samples, including some from the droppings of laying hens in Brazil.

The focus was on genes that make Salmonella resistant to antibiotics, plasmids, and virulence factors. Plasmids are like tiny packages of DNA that can be swapped between bacteria, making them tough to treat. Virulence factors are what make bacteria harmful. The findings showed that many antibiotic resistance genes were present across different Salmonella strains. However, poultry isolates had fewer unique resistance genes compared to human isolates.

Out of 52 resistance genes identified, nearly half were found in both poultry and human samples. About 21% were unique to poultry, and 30. 7% were exclusive to humans. This suggests that poultry might be a significant source of antibiotic-resistant Salmonella. The study also found mutations in genes that make Salmonella resistant to certain antibiotics.

One surprising find was the presence of SPI-10 in S. Braenderup, a genetic element that hadn't been reported before. SGI-1, a known resistance gene carrier, was found in a few S. Schwarzengrund samples from poultry. The CS54 island, another genetic element, was only seen in S. Saintpaul and S. Braenderup.

The study also looked at virulence genes, which are crucial for Salmonella's ability to cause disease. Out of 271 virulence genes, 161 were common across all serovars. The rest were unique to specific serovars, showing a varied distribution pattern. This genetic diversity is a concern because it means some strains might be more dangerous than others.

S. Saintpaul, in particular, had the least variety of plasmids, which could affect its ability to spread resistance genes. The findings highlight the need for better surveillance and control measures in poultry production. This is crucial for public health, especially with the rise of multidrug-resistant strains.

The study sheds light on the genetic potential of often-overlooked Salmonella strains in poultry. These strains pose a significant threat to public health, especially with their resistance to antibiotics used to treat human infections. It's a reminder that the fight against foodborne illnesses is ongoing, and understanding these sneaky bacteria is key to staying one step ahead.

Salmonella's Hidden Threats: Poultry's Secret Fight

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