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New Hope in Fighting COVID-19: Scientists Tweak Molecule Design

Sunday, November 23, 2025
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Scientists are actively working on innovative strategies to combat COVID-19. Their focus is on modifying a special molecule known as N, N'-diphenylurea, which has the potential to inhibit the virus's ability to replicate. However, this molecule presents certain challenges:

  • Poor water solubility
  • Potential harm to cells

New Versions of the Molecule

To address these issues, researchers have created 27 new variants of the molecule. Among these:

  • Seven exhibit improved water solubility.
  • Nine are more effective at preventing viral replication.
  • The most effective variant demonstrates 34% efficacy.

Despite these advancements, a significant challenge remains:

  • Potential harm to cells persists.

The Importance of This Research

This ongoing work is crucial for several reasons:

  • It enhances our understanding of how to develop more effective molecules.
  • These molecules could be instrumental in creating future medications to combat COVID-19.

However, further research is necessary to ensure that these molecules are both safe and effective before they can be used in treatments.

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