healthneutral

Mixing Meds and Drinks: A Risky Combo

USAMonday, December 22, 2025
Advertisement

Mixing medications and alcohol can be a dangerous game. Many people don't realize that even common over-the-counter drugs can react badly with alcohol. This can lead to serious health issues, from liver damage to respiratory problems.

Pain Relievers

Ibuprofen and naproxen, found in brands like Advil and Aleve, can cause stomach bleeds. This risk goes up by about 37 percent when combined with just one drink.

Acetaminophen, known as Tylenol, is even more risky. It can cause liver damage, especially if you drink heavily. The liver works hard to break down both alcohol and acetaminophen, creating a toxic byproduct that can harm the liver.

Cold and Flu Medicines

Alcohol can make you dehydrated, which worsens flu symptoms. It can also enhance the side effects of cough syrups, leading to dizziness and drowsiness. In severe cases, it can even cause breathing problems.

Allergy Medicines

Benadryl can make you feel more drowsy when mixed with alcohol.

Sudafed, a nasal decongestant, can mask the effects of alcohol, making you drink more than you should. This can lead to alcohol poisoning and other health issues.

Antibiotics

Alcohol can make it harder for your body to fight infections and can strain your liver. Some antibiotics, like metronidazole, can cause severe reactions when mixed with alcohol, including vomiting and headaches.

Antidepressants

Alcohol can interfere with how antidepressants work and can make depression worse. It can also impair your judgment and reaction time.

Benzodiazepines

Benzodiazepines, often prescribed for anxiety, are particularly dangerous when mixed with alcohol. Both substances slow down the central nervous system, which can lead to respiratory failure. This combination is a major cause of emergency room visits and accidental overdoses.

Blood Thinners

Both alcohol and blood thinners can prevent blood from clotting, leading to dangerous bleeding. Alcohol can also irritate the stomach lining, causing internal bleeding.

In Short

It's best to avoid alcohol when taking any medication. Always check with your doctor or pharmacist to be sure.

Actions