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Heart Failure Readmissions Rise in Lupus Patients

USASaturday, July 4, 2026
Systemic lupus erythematosus (SLE) is a long‑term autoimmune condition that puts people at higher risk for heart problems. Researchers looked at data from 2016‑2017 to see how SLE affects people who are admitted for heart failure. They studied more than 1. 6 million adults, of whom about 9, 100 also had SLE. The SLE group was younger and mostly female. They also tended to live in poorer areas and had more other illnesses than those without SLE. These differences help explain why their hospital courses were tougher. When the researchers checked how often patients came back to the hospital within 90 days, they found that SLE patients were about 7% more likely to return. Roughly one in three people without SLE came back, compared with almost 41% of those with SLE. In‑hospital death rates were similar for both groups, but the chance of dying after a readmission was almost twice as high. The average stay for SLE patients was four days, the same length of stay as others, but their bills were about 13% higher.
The study also identified factors that raised the risk of readmission. Having Medicaid, being admitted on a weekend, kidney failure, a heart attack, or going home to a facility instead of their own house all increased the odds. On the other hand, women, patients treated at large teaching hospitals, and those with high blood pressure or diabetes were less likely to be readmitted. These findings show that SLE adds extra strain on patients and the health system after a heart failure hospital stay. Care plans that focus on smooth transitions, team follow‑up, and help with social needs could lower readmissions and save money.

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